Liver :: Cirrhosis, Elevated Creatinine And Sovaldi


May 29, 2015

I just need to ask that my father was on sovaldi treatment for 4 days when his (serum) creatinine level shot up to 2.53 which later came down to 1.96 and now at 1.43. He has no renal impairment and his kidney ultrasound and detailed urine report is perfectly normal. He is cirrhotic (Hep-c) at stage 2 according to doc (hep-c) which stopped the sovaldi + ribavirin treatment to save his kidneys. However during the period he was also on diuretics (furosemide) occasionally. His nephrologist says that it is safe to continue sovaldi treatment but the other doc gave a red flag (I have yet to have a discussion with the nephrologist). So I am asking that is it possible that creatinine levels change because of sovaldi or do i need to the change my doc? Also he has edema occasionally. He also has acid reflux.

Age: 58 Sex: M Height: 5'10" Duration: a year (stopped sovaldi: a month) Location: Pakistan Medical Issues: Hep-C, 2nd Stage cirrhosis, acid reflux, depression, anemia Medications: Furosemide (Depending on edema) Rabeprazole (Twice daily half and hour before food) Folic Acid Vitamin-D and Calcium

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