Any Insight To Coming Off Mirtazapine?


Nov 25, 2013

Can anyone give me some insight to coming off mirtazapine?

I've gone from 30 mg for 8 months to 15 mg 9 days ago to 7.5mg 3 days ago.

So far(touch wood) i feel fine but i'm concerned with all the bad experiences some people have had during coming off this drug.

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Did a slow taper off 30mg Mirt. Had nothing for 5 weeks and feeling ok ish. Last couple of days my skin is crawling. Does anyone know if taking a antihistamine will help.

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This is really an update I have cut back on the xanax to .25 down from .05 The mirtazapine sort of helps me sleep.I skipped 2 nights of the xanax and just took the mirtazapine slept ok then came back the next night with .25 mg of xanax with half of a 15mg Mirt. then Back to just the Mirtazapine so far i feel ok just some depression but it is not bad as i express these feelings in a journal form it helps me work them out. I am not feeling any issues

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Coming Off Mirtazapine And Weight Gain

I'm already taking Pristiq however was having episodes of anxiety, panic attacks and insomnia and so my doctor also prescribed me mirtazapine. In some ways it has been a miracle, as somebody suffering from severe social phobia it has helped me to open up a little to the outside world and even attending social outings which is not like me. I feel far less stressed as well. I WISH I could stay on it!

The problem I am having is I've put one a huge amount of weight in the month or so I've been taking it. I've put on at least 7kg but probably more by now, I am visibly much fatter, and being a bit overweight in the first place (and wanting to lose weight) means this far outweighs the benefits. I suddenly have a huge appetite and I cannot control my eating, it is becoming a real problem. I've read people say to get over it and simply control your eating but it isn't that easy, before I even try a strictly healthy diet, I need to get off these pills and give my body a chance to get over these cravings.

My first question is, if I were to stop taking mirtazapine, or even start taking one every 2nd day to eventually taper off, can I expect any awful side effects? I have big exams in a week and I don't want to risk nasty side effects, however I'm really worried I will just keep stacking on the weight even in that short week, I want to get off them ASAP. I haven't been on them all that long so am wondering if I will experience anything bad if I cut back on them. My other antidepressants cause me vertigo if I miss a pill.

Second question, has anyone had any luck with other anti-depressant or anti-anxiety medication that helps with general/social anxiety, that does not cause weight gain? I know everyone reacts to medications differently but I'm just interested to see if there is an alternative to mirtazapine without this one (seemingly very common) side effect. 

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Tips / Experiences - Coming Off Mirtazapine

I have been on 30mg mirtazapine for four years. I tried to come off them a couple of years ago and failed miserably, returning to my full dose after 10 days of awful anxiety and insomnia, as well as migraines and nausea. I had cut my dose to 15mg for a week and then dropped to zero.

This time I read every thread on here about mirtazapine withdrawal and started off really slowly, cutting down by just 3.75mg for two weeks. Then by a further 3.75 mg. At the same time I started taking a lot of inositol. I take a huge heaped teaspoon in my tea every morning. I had only slight nausea when I first started dropping my dose but I think that was me getting used to the inositol. Once I was down to 22.5mg of mirt, with no withdrawal symptoms, I figured I could go a bit faster and dropped my dose down to 15mg. I had no withdrawal symptoms after ten days and so have now dropped my dose to 11.25mg. I use a simple pill cutter from ebay to cut my tablets. So I am now on three quarters of a 15mg tablet. Mirtazapine had pooped out on me and so I already have terrible insomnia. I take temazepam some nights and benadryl on others to help me with that.

I will post my progress here. Who knows, I may fail miserably, but whatever the outcome, I hope it will help others. I was terrified of coming off mirtazapine, but now I am excited by it. I think the key is to take it really slowly and work out the pace your body can cope with. The smaller your dose goes, thee smaller the decrease in your dose should be. Good luck everyone, and please post your own experiences here. I know some people have really suffered despite coming off mirt very slowly. Everyone is different and I think everyone's experience can be a real help to others.

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I am trying desperately to come off mirtazapine and I am trying to work out the best plan to withdraw, 26 days ago I reduced my dose from 30 to 15, although I am bearing it, the side effects are awful, I have a thick headache, nausea, trembling, but to name a few, today I burst into tears for no apparent reason, please can someone tell me if this is normal? I was hoping to cut the dose down by half again, does anyone know if this happens after each reduction ? And when is right time to reduce.

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I have been taking 15mg of mirtazapine for 6 months for sleep problems and anxiety.

It has helped me sleep and feel more relaxed. But have struggled with word retrieval and foggy head. I decided to come off it and have been on 7.5 mg for 4 weeks, I have been doing ok but the last three days have had problems sleep waking after 3 hours and my anxiety feels like it coming back! Is this just withdrawal or am I going back my old ways?

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Currently, my bite is so off to the left side that it is not even funny. I look like Rocky from the movie "Rocky" when he is screaming...."Adrianne!!" and his mouth is sort of way off to one side.

Can anyone out there who has had TMJ Concepts joints replaced lend me any guidance or advice? I am unable to chew and have been on a non chewing diet since March and am only able to open my mouth two fingers and talking hurts quite a bit.

I know I am making the right decision for me as I have been dealing with this for years.

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Mirtazapine :: Tapering Off Mirtazapine - Spinning Myself In Circles

For the first time in a very long time, I'm finally in a good enough place to make the step in coming off my Anti-depressant. I've been on Mirtazapine 45mg for the last 4/5 years and before that a string of various of medications.

Despite my anxiety been kind of excessive at the moment, after a discussion with my GP, he was happy to let me begin tapering down the dose. The problem is with my anxiety I feel it mainly physically rather than mentally so it makes me a little oversensitive to any changes that take place in my body.

I guess what I am searching for is some reassurance so I can stop driving myself up the wall, exhausting google search on mirtazapine withdrawal. 6 nights ago I started my first reduction so 45 mg to 30mg. In all honesty it's not been that bad, a few waves of nausea, headaches and random aches and pains. Those I was expecting so don't mind too much. The trouble is that for the last 3 days, I've found myself a little short of breath for most of the day. It's nothing that's outwardly noticeable at the moment, but it's there and is slightly concerning. Has anyone else experienced this when tapering?

I'm kind of freaked out a little because one of my fears that's arisen since the mirtazapine is the that i will develop random allergies and my brain is wondering if I've suddenly developed an allergy to my meds (ridiculous, I know!) The other thing is that the rest of my family has had either viral chest problems lately so maybe I've just picked up that and it's a coincidence? Or it could just be the anxiety.

I'm totally spinning myself in circles at the moment so any wise words are most welcome at this point. If I know it is just withdrawal and nothing that can actually hurt me then I'm fine with whatever effects it throws at me.

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I was initially on(30mg) for 8 weeks for depression and anxiety. And I did start to feel better, although the blurry vision and the derealisation side effects started to make me anxious again. I think the light head was the anxiety not the tablets.

Went back to work and made an appointment with the Doctor to see if there was another antidepressant with no side effects as I didn't think the Mirt was working.

He told me how to gradually come off the Mirtazapine and then to start Those days coming off the Mirtazapine were fine and the 3 days I took nothing I felt great again! Well what an awful reaction I had to the Citalopram ! Heart thumping, sickness, mind racing, pins and needles, total insomnia for 3 days and the anxiety attacks were awful! I actually phoned NHS Direct.

When I spoke to the Doctor , he said that I had a reaction and the tablets obviously didn't agree. In a knowing smile, he said that I should perhaps go back on the Mirt and that I came off them too quickly.

I am now on no medication , but can feel the awful anxiety still there from the Citalopram episode and am wondering if I will slip back to square one again if I don't take anything. The Doctor has given me a prescription for 15mg 1 week and thereafter 30mg. Perhaps the side effects weren't that bad and as the nurse said " only got bothersome because I was feeling better".

So I'm thinking that I will go back to the Mirtazapine and perhaps they aren't that bad!

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