Brain Damage - Mixing Opiates/opioids And Alcohol Together


May 17, 2014

I am now been abstinence from substance-abuse. For 2 years, I was mixing opiates/opioids and alcohol together, and sometimes I mixed other substances with those-including cocaine. Plus, I already have depression and anxiety. I have been to a treatment/health care center twice. First time of abstinence, for 2 weeks I couldn't speak right. I'd think of a sentence. I'd start to say the first few words-with a stutter-and then forget the sentence. I would have to start my think process over again a couple of times.

I continued using/mixing-if not more-and became dependent on opiates/opioids, and I had already been diagnosed an alcoholic. I became abstinence, and still am. It's been about over 2 months of no substance abuse. I developed unnecessary stops in my sentences while I speak. Like my brain can't catch up to my speech while I talk, causing me to have to stop for a very short time before continuing me sentences-this can happen a few times in one sentence. I still have to restart my thinking process over again because my mind goes blank while trying to speak. When there are things that distract me or someone speaks a little bit while I'm talking, I have to restart my thinking process all over again.

Some other things that are going on with me is that I often feel microscopic bugs crawling on me and biting me. I also sometimes become frightened because I sometimes see shadows in the corner of my eyes or behind me. While staying still, my leg or arm will sometimes randomly jerk-I'm not doing it, my body is doing it by itself. I also forget to breath, and I have to remind myself to breath by myself.

I want feedback of what you'd think these are symptoms would be of, and/or if this is more of a severe or minor thing. Drug-induced brain damage?

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Briefly: I was a social drinker for 25 years, occasionally drinking more than I should have (but at things like celebrations and functions).

Two years ago, I began to develop mental health problems, but didn't start drinking more heavily (self-medicating) until about one year ago, when I also started to binge drink occasionally, including twice last October.  After a gap, I then restarted drinking heavily in March this year, and this became very heavy at times in the summer (80+ units per week), with occasional even heavier binges, the most recent being last Thursday / Friday (50+ units each day).

I finally ended-up in hospital last weekend with tachycardia, low blood pressure and probably alcohol poisoning.  While there, I first developed a painful red/purple rash on my chest.  I was put on antibiotics for this, and it seems to be clearing-up.

However, then, I quickly developed various other strange and unpleasant physical symptoms:

- numerous bruises;

- numerous pimples and red/purple dots under the skin;

- some hair loss and extensive hair-thinning;

- a spider naevus;

- red palms;

- itchy skin- skin darkening affecting the backs of my hands and genitals;

- regular, profuse sweating;

- whites of eyes turned lemon;

- brain "fog".

Some of these symptoms have reduced or resolved (eg. red palms and itchy skin), but the others have persisted.

I am eating OK, but making an effort to do so.  In spite of this, I have lost about a stone in weight in the past 3 weeks.  I'm also lacking in energy.

Since June, I have had regular liver function tests and other blood tests, too.

These have shown elevated enzymes, more or less in line with the extent of my drinking.  In early August, after a serious binge, the AST was 96 and GGT was 121.  In mid-August, AST had reduced to 25 and GGT 72.  But they were higher again (though both under 100) on my admission to hospital last weekend, but had started to fall again after I was there for a few days.  I have been advised that, in all of the tests, the values for other important measures were consistently normal.  The junior doctor in hospital said the LFTs indicated no cirrhosis or hepatitis. 

I also had a physical exam (just manual) from a GP in mid-August, and she said my liver / abdomen felt soft and suple with no sign of inflammation, enlargement or hardness.

However, given the strange and unpleasant physical symptoms that quickly developed in hospital last weekend, I fear that my last serious binge a week ago finally tipped me over the edge and into serious liver disease.  Too many of the symptoms are those of cirrhosis for me to think anything else.  (I've checked on the NHS website.)

I am absolutely terrified that, despite good advice and warnings, I did not take heed and my body, especially the liver, has finally been permanently damaged by the alcohol.

My main question is: can I turn things around?  I have not had anything to drink since last Friday, and have no inclination to do so.  I am drinking a lot of water, fruit and vegetable juices, and eating healthily.  I will try to get some exercise, though I don't have much energy.

I'll see my regular GP next week, but could do with some advice and, if it's appropriate, some reassurance before then.

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Narcotic/Opioids Withdrawal And Testosterone

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now to the "juicy" stuff. I'm not a doctor and i do not know how this impacts females as hormones in both sexes act very differently. that being said, take this information with a grain of salt. I am a Male speaking from personal experience.

Testosterone is the king of all hormones, specifically in males....it is made in the testes and is responsible for emotions, sex drive, attitude, appetite, energy, sleep and so forth. that piece of information is key as this will help you understand some of the withdrawal symptoms. NOW, during the use of opiates for extended amounts of time, testosterone levels and production are seriously depleted ..which results in lower sex drive, less energy and motivation, etc. SO, when you stop taking opiates and endure the withdrawals, your body will be rebooting itself, there will be a lack of balance of your total biology for some time.

this is where my experience played a role in my understanding of what happens to the body during detox. after a week of withdrawals, i began experiencing restlessness, break outs and really oily skin on my face, and energy i didn't know what to do with. because my body was out of balance, i was in a state of "limbo": i was energetic and tired at the same time. i talked to my doctor and as it turns out, my testosterone levels were Through the Roof! upon detox, and opiates out of my system, by body began producing testosterone at near dangerous levels...its like going through puberty again! now...this is both good and bad. too much testosterone can result in the possibility of testicular cancer, and this isn't me trying to scare you...every single individuals experience varies, no two are alike. anyway...now for the good news. after a week of being lethargic yet restless and having little sleep, i forced myself to go to the gym. BEST DECISION EVER. your body is producing all this testosterone post-opiates, might as well put it to use. i KNOW how it feels to get up and drag ur arss to the gym, but i promise you that it will be revitalizing. 

i did some basic stretching and work outs and got myself some heavy duty protein. i also learned that testosterone is most easily and directly distributed to your legs which could be a factor that plays a role in RLS. think about it, testosterone production sky rockets, testosterone is responsible for energy, you're not putting that energy to use and therefore drives ur legs crazy when all you do is lay around and do a whole lot of nothing. anyway, i did some basic work outs, came home, loaded up on vitamins and drank a nutritious protein shake and that night, i slept like a Rock. the next day i felt like a million bucks...but because i've been on methadone for a year, to this day (37 days post methadone) i still experience very very mild but noticeable symptoms of w/d (hot flashes and stuff).

after FORCING myself to get up and go to the gym, i've gotten out of my state of "limbo" i am energetic during the day and sleep significantly better at night. 

The KEY here is: know your body, understand it. you may be sober, but FAR from normal. so it is crucial to do whatever it takes to help your body regain that balance.

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Once the drugs were no longer in my system (and I mean months, If not a year to fully regain my sanity of overcoming this) I was able to get my life back.

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