Mirtazapine :: Losing Weight When You Come Off It?


Oct 18, 2014

I have been on Mirtazapine for 20 months. When I first started at the 15mg dose, in a month I gained a stone. Then dieted and lost it. I have never had a problem losing weight over the years by eating a healthy diet. Usually losing 2 stone in 3 months, Now on 30mg of mirtazapine, was on 45mg but had unusual highs so it got reduced. Since September 2012 I have gone from 10 stone to 14 stone 9 and I have dieted in between with not much luck. I dieted for 4 months and lost 4 pounds and I was eating so healthily and almost suffering. Due to being a victim of crime 6 weeks ago I come off the diet due to stress.I cannot control the hunger and cravings. i binge to the extreme between 10pm and 2am, I even eat in my sleep.

What worries me though is even on a diet I cannot lose the weight. And as I say, in the past I have lost weight when eating healthily no problem.

My doctor wants to start reducing my mirtazapine in January as I am on too much medication. I am worried about coming off it as I have gone through anti depressant withdrawal before, actually paroxetine withdrawal is the reason why I am on mirtazapine, Plus for my height and now weight I am obese so that is the other reason he wants to take me off it.

I just wondered if anyone has had weight gain and if they have lost it when they stopped mirtazapine?

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Mirtazapine :: Weight Gain / Loss

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I hadn't been sleeping that well after the last increase to 45mg at night. What I did notice is that my hunger was out of control and I was eating in the middle of the night and in the morning (which I never did before). I felt like I was gaining weight, and felt out of control from the frequent eating. This was the EXACT OPPOSITE of what I had wanted.

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Today I have been given 15mg Mirtazapine for the first time. From reading reviews I'm very concerned about taking them mainly due to the weight gain many people experienced.

I'm a 31 year old female and other than the past 2 years I have always been overweight (18 stone). I'm now 11 stone which I'm comfortable with.

I have been given Mirtazapine as following operations and maybe more to come I have been suffering with very low self esteem mentally & physically. 

I know the medication has been given to help but I'm worried if I am to gain weight I will feel even lower about myself. I have told this to my GP who has advised he will weigh me in 2 months to see if weight has been gained.

By reading your reviews the weight gain seems to happen very rapidly.

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I'm already taking Pristiq however was having episodes of anxiety, panic attacks and insomnia and so my doctor also prescribed me mirtazapine. In some ways it has been a miracle, as somebody suffering from severe social phobia it has helped me to open up a little to the outside world and even attending social outings which is not like me. I feel far less stressed as well. I WISH I could stay on it!

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My first question is, if I were to stop taking mirtazapine, or even start taking one every 2nd day to eventually taper off, can I expect any awful side effects? I have big exams in a week and I don't want to risk nasty side effects, however I'm really worried I will just keep stacking on the weight even in that short week, I want to get off them ASAP. I haven't been on them all that long so am wondering if I will experience anything bad if I cut back on them. My other antidepressants cause me vertigo if I miss a pill.

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I am a very active guy, I play football twice a week and do lots of cardio but it seems whatever I eat, it goes straight to my belly. This has pretty much always been the case with me throughout my life.

I think I was roughly 15.5 stone when I started on Mirtazapine in July 2014 but I now weigh roughly 17.5 stone. I am 6ft7 in height so I guess I needed to put on a few pounds (as I was quite slim previously) but 2 stone is a rather big weight gain.

For an unknown reason I always feel hungriest late at night, does anyone else get this symptom? I take the tablet every night before I go to sleep (around 10:30pm).

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