Duloxetine :: Light Sensitivity With Pupils Dilated And Racing Heart


Aug 2, 2014

I have taken my first Duloxetine 30mg. it has totally disorientate me, my eyes are badly reacting to light. my heart is really racing. my pupils are dilated. I feel as though my body is running at a very fast pace.  I have not been able to sleep at all last night.  I took my tablet at about 3pm in the afternoon.  I did not take a second one today as my symptoms have not dissipated at all and yet the tablet must be well out of my system as it is 32 hours later now.    I have made appointment to see my doctor but it is not for another 4 days. what do I do in the meantime to get rid of this awful feeling.  I know i will not sleep tonight.  My body is racing and I have a lot of energy.

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Duloxetine :: Dilated Pupils

Right i decided to wait for stag dos to be finished. Now on day 3 of duloxetine. I have nausea and very tired effects kicking in alongside dilated pupils. Does this subside after time, i never felt this bad on any antidepressants.

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Alternative Therapies :: Photophobia / Light Sensitivity - Actually Able To Walk Around Outside

I have had extremely bad photophobia for the last 3 yrs (sunglasses in house etc), which started after having my eyes dilated 4 times. I don't have any eye disease.  However 3 days ago I bought a herb (which i read about on the internet), called qi ju di huang wan. They are tiny little black pills and you take 30 a day. And I am actually able to walk around outside now without my sunglasses even in the sun!!!! (still best to wear em though).

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Corneal Ulcer :: Blurry Vision And Sensitivity To Light

Hi everyone, just after some advice.. My left eye started watering really bad last Wednesday, by the Friday the white of my eye was blood red, I arranged a visit to the GP who gave me chloramphenicol eye drops and if it got any worse to take myself to our local eye hospital. By the Sunday my eye was so painful, watering, bright red and light sensitive. I ended up visiting the eye hospital to be advised that I had an ulcer on my cornea. This us down to a viral infection, I was given antiviral eye ointment to put in 5 times a day for 10 days. The doc said due to my job I would probably need 2-3 days off. 

I have been off 3 days now and although the pain and redness has calmed down, my eye is very sensitive to light and my sight is still blurry.

has anyone else suffered this please and how long did it take to recover and the eye to feel normal?

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Mini Migraines :: Without Aura, Body And Ear Pains With Light Sensitivity

I've had migraines a good chunk of my life and I haven't had one in roughly 9 months but I have been experiencing almost like mini migraines? in that I experience pain very similar to a migraine but without the aura or having to lie down or take it seriously. I guess these could be tension headaches, but I'm not sure? I've also been experience other symptoms, including: ear pain, sensitivity to light/sound, ringing in the ears, and various pains all over my body. these symptoms can happen with a migraine but lately they've been constant and if not, happening often enough that I'm noticing. I've had a brain scan and nothing. I don't think it's ever been like this before and I'm curious as to what it could be? As in, a starting point. I do have migraine medication but all it does is put me to sleep, it doesn't help with the pain. Not sure if that matters.

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Nervous System :: Head Pressure, Eye Floaters, Light Sensitivity

I have an undiagnosed condition which started three years ago, in December 2009. My family doctor doesn't take me seriously, so I am switching to another doctor soon. I'm male, 26 years old, non-smoker & non-drinker. Blood pressure on average 130/80, pulse rate around 70. I am 6 foot 1 tall, and weigh around 214 pounds (97 kg).

My symptoms:-

- Head pressure (especially around the temples)

- Feeling my heartbeat pounding in my head (i don't hear it, but i definitely feel it)

- Massive eye floaters in both eyes (always present)

- Light sensitivity (always present)

- Slight blurry vision from time to time (depending on the severity of the "head pressure")

- Eye pain (also depending on the severity of the "head pressure")


What makes it worse:-

- When I eat something very salty

- When I am very nervous, or very angry


What makes it better:-

- When I press on my temples

- When I tie a piece of cloth around my head

- Diazepam 5mg


Worth mentioning:-

- No fatigue (i have a lot of strength & energy)

- No appetite loss

- No sleep problems

A detailed history of my condition:My problem began in December 2009 as just a strange feeling in my head. I started to literally feel my pulse pounding inside my head. This was accompanied by a feeling of pressure in the head, especially around the temples and around the eyes. It felt like extremely high blood pressure, but only in the head. I ignored all of this, thinking it's something that will go away quickly, but I was wrong.
After a couple of months, in the spring of 2010, the head pressure decreased somewhat, but then I began to have eye problems. There was a dull tension-type pain, first in my right eye, then in my left eye. This type of eye pain is very difficult to describe: A strong tension/pressure type of pain, which feels exactly like the pressure in the entire head. This lasted for several days, and then comes the worst part: massive eye floaters in both eyes, accompanied with light sensitivity. The eye pain went away, but the floaters & light sensitivity remained, as well as the head pressure. The floaters & light sensitivity are always present, 24/7, so it's definitely not a migraine.

The problem "stabilized" in the summer of 2010, and remained very stable or "tolerable" I should say. Head pressure reduced by more than 50%, no eye pain, and only 5 or 6 floaters. Then in October 2012, for unexplained reasons, the whole thing came back with a punch. The pulse pounding in the head, the head pressure, and the eye pain all increased about threefold. Then a few days later, new eye floaters came along (more than 10 new floaters!). Now the whole thing is somewhat stable, but definitely not as good as it was before.

Why was it "ok" for more than two years, and then came back like this? The only thing I can think of is bodybuilding. In October 2012 I began to lift weights, mostly benchpress, and about a week after that, the problems began to intensify. This is the only thing I can think of that might have played a role.

Here are the exams I have had done in the past few months:-

- Extensive blood work, including TSH test (thyroid function): all clear, except for somewhat high cholesterol (255)

- Abdominal ultrasound: completely normal

- Ophthalmoscopy with dilated pupils: no retinal tears, no holes, no damaged blood vessels

- VEP (Visual Evoked Potential) test: completely normal

- Carotid doppler ultrasound: completely normal (I really insisted on the carotid doppler ultrasound, because of the feeling of high blood pressure in the head.)

I didn't have health insurance for a long time, which is why I started to see doctors only a few months ago. Now, I have learned to control this condition by avoiding salty foods, avoiding stress, and avoiding weightlifting. By "controlling" the condition I mean preventing it from getting worse. But nonetheless I want to know, and absolutely have to know, what is causing this problem, and how to treat it.My family doctor does not want to do an MRI or a CT scan. He thinks this is all stress related without any physiological causes whatsoever, which I think is completely absurd, and this is the reason why I'm switching to another doctor very soon. In any case, my questions are as follows:

1.) Is it possible that these symptoms could be caused by a deformity of the neck and/or the spine? I have had a really terrible posture since I was a little kid, but my family doctor (as well as my neurologist) dismisses this idea, saying there's no chance it could cause these problems.

2.) Is it worth doing a contrast-enhanced thyroid ultrasound?

3.) Should I do an electrocardiogram & treadmill stress test?

4.) What medical exams would you recommend me? MRI? CT? If so, exactly what kind of MRI? Cervical? Head only? Whole body? I really don't know much about this subject.

5.) Is it possible for the eyes to really be healthy, but for a person still to experience floaters & light sensitivity, for example because of something neurological?

If there is anything at all you could say about this topic, I would really appreciate it. To this day I am not able to find on the internet one disease that has all of these symptoms. The whole thing really feels as if the blood pressure in my head is extremely high, but obviously that's not it. I would very much like to know if you were in my shoes, what exams you would like to have done.

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Pituitary :: Adrenal Crisis - Brain Fog, Light Sensitivity, Blurred Vision, Weakness

Hi, I’m hoping some people can hopefully give me some advice please regarding treatment. My history: I’m 30, diagnosed with secondary adrenal insufficiency via an insulin tolerance test. I have borderline low hypothyroidism, low prolactin. No cysts. I am 40kg, 5ft tall so I am very petite.

I currently take hydrocortisone after each meal 8am-4 mg, 12m-4mg, 3.30pm-4mg, 8pm- 3 mg. I have to take my medication following food to reduce the intensity of the spike. I also cannot tolerate more than 5mg at one time without getting awful side effects of anxiety and panic when the tablet peaks in my blood at 30 minutes. Each doe I take only lasts around 2.5-3 hours.If I am to take 10mg at once I feel ‘high’ and ‘rushy’ and anxious when it kicks in then after 3 hours its starts to drop and I feel low cortisol again.

I feel like I am swinging all day every day. I am still so fatigued, have very bad dizziness and brain fog, light sensitivity, blurred vision, weakness, leg and arm cramps, reactive hypoglycemia and achy.

4 weeks ago I ended up having an adrenal crises, yes it was horrendous and scary but I got through it and in a way it  was a blessing because it has been a BIG wake up call that I need to stop being scared of trying new medication in fear of getting sicker and realised I have got to try and get myself well.

I have been so unwell since I was 21 I am now 30. ….i have lost so much of my life and I am sacred I am never going to get better or managed.

My consultant prescribes medrol a while ago and I have been too scared to start to but after my crises I started it.  I am now taking 1mg Medrol in the morning and then 3 more doses of hydrocortisone at 4mg, 4mg and 2.5mg…

When I first started the Medrol I could feel it working but now its like I can not feel it and by 4 hours later I am feeling hypoglycaemic, weak nauseas etc…  I am feeling so unwell after I eat a meal, like all my bodies energy is wiped out from digesting my food and im now lying in bed weak, giddy and lots of pain cramps in my arms and legs…

I have low blood pressure and my consultants suggested

fludrocortisone.  I just don’t know what to do anymore.  My consultants saying I shouldn’t feel so unwell and im just so lost.

Has anyone been on Medrol and can give advice on this.  Im very petite, 5ft and 40 kg…I just feel so up and down and struggling with it all and also feel my symptoms get worse or better during certain times of the month..

i also cannot tolerate many carbohydrates because my blood glucose pikes very high at 1 1/2 hours post eating and drops every low by 21/2-3 hours.

I’ve now had to set up a backup carer to help when am unwell because i am on my own with 2 young children.  I am getting help with them now and also trying to get support for taking them to school…im slowly getting there

I have also done a month of blood tests looking at progesterone and  estrogen and have found a pattern in some of my symptoms..  I most definitely feel my worst when I am coming off my period, stopping bleeding where I start to feel cold and foggy and nauseous I then when ovulating feel at my worst and the 2 days when my estrogen was highest I had severe anxiety, tremor, agoraphobia, intense drowsiness after eating and these symptoms always disappear once I ovulate and start seeing progesterone mucous .  Apart from these symptoms which come on with my cycle I suffer with all my other symptoms throughout the whole month with increase and decrease throughout my cycle.

I have included a lot of tests below and anyone who feels they can help would be so much appreciated. Thank you for your time

These are my most recent blood test

June 20th 2014

Autoimmune profile – normal no action

Mitochondrial antibody level – negative

Anti-smooth muscle autoantibodies – negative

Panetta cell autoantibodies – negative

Reticulum antibody titre – negative

Anti-liver kidney micro ab lev – negative

Serum vitamin D – 71 nmol/l

Erythrocyte sedimentation rate – 9 mm/h (0-15)

Total white cell count - 6.5 10*9/L (3.5-10.0010*9/L)

Red blood cell count -  4.14 10*12/L (3.8-5.0010*12/L)

Haemoglobin estimation - 119g/L (115.00-145.00g/L)

Haematocrit - 0.360L/L (0.36-0.46L/L)

Mean Corpuscular volume (MCV)  - 87Fl (84-98)

Mean Corusc. Haemoglobin (MCH)  - 28.7pg (27.5-32)

Mean Corpusc. HB conc (MCHC)  - 331g/L (300-360)

Red cell distribution width - 15.1% (<14.50%)

Platelet count - 194  10.9/L (150-400 0010*9/L)

Neutrophil count 3.3 -  10.9/L (1-3.5010*9/L)

Lymphocyte count  - 2.0 10*9/l (1-3.5010*9/L)

Monocyte count 0.8   -  10.9/L  (0.31.0010*9/L)

Eosinophil count -  0.3   10*9/L  (<0.401089/L)

Basophil count  -  0.1  10*9/L (<0.1010*9/L)

Serum folate -  4ug/L  (3-20)

Serum ferritin  - 8ug/L (10-200)

Vitamin B12  - 632 ng/L (200-910)

TSH  - 3.04  mu/L (0.35-5)

Free T4  - 11pmol/L (9-22)

Liver function tests

Total bilirubin level  - 7umol/L (1-21)

ALT  -  9 U/L (1-50)

Blood calcium level  2.16 mmol//L

Corrected serum calcium level – 2.14 mmol/L (2.20-2.60)

Serum inorganic phosphate  - 1.44mmol/L (0.8-1.50)

Serum alkaline phosphatase – 54 U/L (30-130)

Serum total protein 69 g/L (60-80)

Serum albumin  - 40 g/L  (35-50)

Serum globulin  - 29 g/L(22-40)

Serum sodium   - 136 mmol/L (133-146)

Serum potassium  - 4mmol (3.5-5.3)

Serum urea level  - 3.8 (2.50-7.8)

Serum creatinine  - 49 umol/L (20-103)

Plasma C reactive protein   - 0.3mg/L (<5.00mg/l)









I paid for a whole series of blood tests.  They was taken on day 4 of my period, I had fasted for 12 hours. I was salt fasted for 24 hours and remained sitting up prior to the test and during the test so the aldosterone and renin tests were accurate. The bloods were taken at 9am. I take hydrocortisone 15mg a day and took my last dose of 2.5mg at 8pm the night before the test. I was taking no supplimenst or anything else around the time of the test.

 HORMONE PROFILE

Aldosterone 399.0 pmol/L Upright 100 - 800 pmol/L Supine 100 - 8450pmol/L

RENIN 66.2 mU/L Upright 5.4 - 60 mU/L    Supine 5.4 - 30 mU/L

Aldosterone: Renin ratio 6    <80 Conn's Unlikely

FSH  6.1 U/L

LH 11.9

Oestradiol 106 pmol/L

Prolactin 144 mU/L 102 - 496

Cortisol (basal) 449 nmol/L (171 - 536) (BASAL 171-536, EVENING 64 - 327)

Free T3 4.8 pmol/L (3.1 - 6.8)

Thyroid stimulating hormone 2.310 mU/L (0.270 -4.200)

Free T4 14.0 pmol/L (12 - 22) 

FULL BLOOD COUNT

WBC 4.90 x10^9/L (4.0 - 11.0)

RBC 4.43 x10^12/L (3.80 -5.80)

Haemoglobin 135 g/L (120 - 150) R

HCT 0.41 ratio (0.36 -0.46)

MCV 93.0 fL (80.0 -100.0)

MCH 30.4 pg (27.0 -32.0)

MCHC 326 g/L (315 - 345)

Platelets 241 x10^9/L (140 - 440)

RDW 11.8 (0.0 - 14.0) **

MPV 9.3 fL

Neutrophils(Abs) 2.58 10^9/L (2.0 - 7.5)

Lymphocytes (Abs) 1.69 10^9/L (1.5 - 4.0)

Monocytes (Abs) 0.44 10^9/L (0.2 - 0.8)

Eosinophils (Abs) 0.22 10^9/L (0.0 - 0.4)

Basophils (Abs) 0.02 10^9/L (0 - 0.1)

CRP< 0.3 mg/L (0 - 5)

BIOCHEMISTRY

Sodium 139 mmol/L (133 - 146)

Potassium 4.2 mmol/L (3.5 - 5.3)

Urea 4.9 mmol/L (2.8 - 7.8)

Creatinine 56 umol/L (45 - 84)

estimated GFR (eGFR) >90 ml/min

LIVER FUNCTION TEST

Total bilirubin 5 umol/L (0 - 21)

Alkaline phosphatase (ALP) 65 Iu/L (30 - 130)

ALT 11 Iu/L (0 - 33)

GGT 8 Iu/L (UP TO 40)

Total Protein 78 g/L (60 - 80)

Albumin 49 g/L (35 - 50)

Globulin 29 g/L (18 - 35)

AST 16 Iu/L (UP TO 32)

Lactate dehydrogenase 171 Iu/L (135 - 214)

Serum Calcium 2.39 mmol/L (2.2 - 2.6)

Albumin 49 g/L (35 - 50)

Adjusted Calcium 2.30 mmol/L (2.20 -2.60)

Uric Acid 278 umol/L (140 - 360)

Glucose 3.8 mmol/L (4.2 - 6.1) **

LIPID PROFILE

Cholesterol 3.94 mmol/L (0.0 - 5.2)

Triglycerides 0.54 mmol/L (2.26) *

HDL cholesterol 1.41 mmol/L (> 1.68)

Cholesterol/HDL ratio 2.8 ( <5)

Low density lipoprotein 2.28 mmol/L (2.5 - 4.5) **

% HDL/Total Cholesterol 35.79 %

B12 687 ng/L (191 - 663) **

Folate (serum) 5.4 ug/L (4.6 - 18.7)

IRON AND UIBC

UIBC 60.0 umol/L

Iron 17.0 umol/L (6.6 - 30.4)

Total iron binding Capacity 77.0 umol/L (41-77)

Transferrin saturation 22.1 % (20-55)

Ferritin 13.1 ug/L (13 - 400)

Ferritin 13.1 ug/L (13 - 400)

Vitamin D 24.5 nmol/L Reported

<25 nmol/L: Severe Vitamin D deficiency

25-75 nmol/L:Borderline ranging to insufficiency

75-200 nmol/L: Optimally replete

>250 nmol/L:Possible toxicity, if sustained

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Panic Attack - Nausea Hot Racing Heart Thoughts Of A Heart Attack

I'm sat with family & friends in my local pub and I'm panicking! Nausea hot racing heart thoughts of a heart attack!

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Trimethoprim :: Racing Heart And Anxiety

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Here I am again like a broken record but just don't know what to do. I woke up today nervous and jumpy. I was so nervous that I made my heart race and called the paramedics. I felt fine once they got to me which in turn made me feel like a crazy person yet again. I have called the paramedics or ran to the ER so many times that I'm scared they won't come when I really need them. I just can't help it. When these crazy feelings come on the anxiety just overwhelms me. The fluttering in my chest, the internal tremors, weird head feelings, the flu feelings, the fluctuating body temperatures is just all overwhelming. Today I just can't seem to shake this nervous and jittery feeling. I ended up turning around to come back home on my way to work. I just didn't want my coworkers to see me acting like a crazy lady today.

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I did notice today that I had a monster migraine when I got to work.  I was anticipating a very stressful day at work (it was fine though) and after I got home and had dinner - my headache was gone.

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I've bin told by people that smoke it too that it will go soon, I just want to make sure.

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My concern is that it has been 7 weeks since my last infusion and I am bruising more than ever. ..I brush by something and get a big bruise. I'm embarrassed to wear shorts...I'm not as tired as before and no more heart palpitations. I had an appt for a follow up last week and they did more blood work to recheck my iron and B12 levels. I should have the results monday. BUT my concern is all of these bruises...what could be going on? I've been tested for some genetic iron disorder and that was negative as well as the other disorder (I forget the name---it mainly affects those of Mediterranean descent ).

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Just wondering if anyone has similar symptoms or would have any suggestions... To add to this, I am 24 years old, non-smoker, don't drink and my BMI is within range.  Doctors have not been able to help me and most of them don't understand that this is completely preventing me from living a normal life. I get light headed and dizzy if I try to exercise, walk up the stairs, go in an elevator, turn too fast or sometimes it happens from just sitting and not moving. Usually my heart rate is part of the symptoms and it becomes elevated spontaneously.

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