Severe Allergic Reaction To Cyclizine

Jan 26, 2016

After reading all these posts about Cyclizine, I feel I should add my own traumatic experience from 7 years ago:

(I now know that I am severely allergic to Cyclizine).

Back in the ward after breast cancer surgery with two visitors at my bedside, I suddenly began to feel nauseous.  Unable to move my head at the time, I asked a number of times if I could have a 'sick bowl' handy as I felt I was going to be sick.  No-one seemed to hear my plea, even though there were lots of medical staff and visitors around in this busy ward.  I felt I was speaking loudly but my request still went unanswered.  I summoned up the strength to really shout out Please, I need a sick bowl - I think I'm going to be sick.  Next thing I saw the nurse half way down the bed putting a needle into the back of my right hand.  I asked her what it was for and she replied "Just something to stop you feeling sick".  Within seconds of that a strong wave of something went through my head and through every part of me.  I started to feel as though my whole body was like jelly and (just as one other poster has described) felt as though I was drowning, couldn't breathe and literally felt as though the life was rapidly draining out of me.

Although I couldn't move my head (or any part of my body), I could see just in front of me and was aware that the woman in the bed opposite me was sitting up and staring at me, as was her visitor.  I wanted to shout out Stop Staring at Me, What are you looking at .... but the words wouldn't come out.  

There was a rush of panic all around my bed, with doctors having been called and nurses running around but at this stage I couldn't see what was going on - only hear.   I heard to my left what I recognised to be the Sister's voice (from having spoken with her earlier) - shouting angrily "Who turned this off?"  She was obviously referring to whatever machine I had been attached to there - which had apparently turned itself off!

Then I remember another nurse's voice which I recognized very clearly as an American nurse that I had been chatting and joking with earlier.  Although I couldn't see her, I knew it was her because I recognized her loud Texan drawl.  She was also the nurse who I had seen (with my tunnel vision) put the needle into my hand.  I do believe now that it was her voice that saved my life.  Her voice was all I could hear at this stage.  She was obviously very close right in front of my face and I remember she kept repeating abruptly and loud:  "Don't close your eyes - KEEP YOUR EYES OPEN!"  My eyes felt so very very heavy and they kept closing.  I so badly wanted to keep them closed - but then her loud voice would bark out the order again "OPEN YOUR EYES!"  and with all the strength I could muster I forced them to open each time.  It was very hard to do, like I needed a bulldozer to get them to open ...  but I managed to do so, only because I could tell from the urgency in her voice that I HAD TO keep those eyes open.

I was also aware that I had been given an oxygen mask and at this stage must have been coming around.  The "jelly" feeling had gone and I remember feeling my nose was itchy under the mask.  I wanted to scratch it but couldn't move my hands.  I'm not sure how long all this was going on, but when the panic was all over I remember the Sister then telling me that I should add 'CYCLIZINE' to my list of allergies.  (I am also allergic to Penicillin (as well as some other antibiotics), and this is something I already knew).

I'm not sure that CYCLIZINE should be banned altogether, as it is obviously something that is helpful to others (in the same way as Penicillin is to others), but I do think it should come under the same category as Penicillin and perhaps some sort of pre-test should be done before administering the drug. 

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Trimethoprim :: Allergic Reaction

I was prescribed this drug yesterday for a supposed urine infection. I had suffered with urine infections alot in my teens and into adulthood, however had not had an infection since having my son 8 years ago. I had problems during my pregnancy high blood pressure being one of these problems. As a result I only have one fully functional kidney. I was told that my blood pressure would probably go up again in later life and therefore have had it checked each year since.

On a routine checkup a couple of weeks ago, it appears that the high blood pressure is back and at the checkup I also had my urine dipped. The nurse asked me if I had any problems passing water etc. When I said I hadn't, she said there was something in my water and would send it off to the hospital just in case. I said that I thought I would have noticed if there had been a problem.

Anyway, yesterday I got the results and the surgery informed me that my doctor had left a prescription out for me. I picked it up and took the first tablet at four o'clock. By seven o'clock I had a severe headache, and the most awful chest pain, I thought I was having a heart attack

On reading the side effects we rang the hospital, got an appointment, by which time my back and chest were covered in a rash. My Blood pressure had reached 240/140 extremely high....

The doctor confirmed that it was an allergic reaction to trimethoprim and injected me with an antihistamine. Having checked my urine again, they said I did not have an infection in the first instance and should never have been prescribed this drug and confirmed that it could have been fatal.

I am going to make a formal complaint to my doctor and would like to take this further. Why is this drug being prescribed? I think I am very lucky to be here today and my children could have been left without their mum.

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Cyclizine :: Very Bad Reaction - Anyone Else?

I went in Macmillan hospital for an Iron Infusion, as chronic anemic. I had the iron, and the then administors Cyclizine via IV, i was resting in reclined position on the chair. Suddenly almost not long after maybe 5 mins as if i was either having a heart or stroke, i was struggling to breath serious chest pains,i don't know what my heart rate was since i have Tachycardia, i can say my heart was pounding and chest wall was very fast, i thought i was having  a cardiac arrest. Bp from 126 shot up 186/90, i would not speak, my eyes were dialated, my eyes were reported by the nurse as "rolling back in my head", i felt as if paralysed as i could not lift my hands or head, i could not call help. I had tears rolling down my face,it was a few minutes before i could talk. It was the most awful, shocking,distressing,alarming,horrible,frightening experience, to have gone through. To add insult to injury i was sent home, and when i called the Dr acted as if he had never heard of this sort of serious reaction. Not a single note in my after care summary, now covering up. Not a single note about i had no warning about possible side effects, the care has had many failures.

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Trimethoprim :: Allergic Reaction - Spaced Out And Hungry

I too have had a bad allergic reaction to Trimethoprim. Within one day of taking the first tablet I felt completley 'spaced out' extremely hungry but could only stand wet food ie soup or yoghurt. On the third day the itching started and a rash developed. Stopped taking tablets and the rash has got progressively worse. Terribly itchy sore and looks as though I have been scalded.

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Penis :: Allergic Reaction To Baby Oil During Intercourse

I was having vagina intercourse with my wife when we decided to give anal a try. I used normal baby oil the one used on hair or whatever the normal use is. I used this baby oil as a lube to insert my penis into her anus. this was on a Saturday then the next day Sunday early Monday I noticed my penis head was red it had small red dots(bumps) all over it and that my wife as well had some sort of redness and swollen to her vaginal area. I like to think this swollen penis head and red dots are from a allergic reaction to the oil or from the anal sex but I would like to know the likelihood of this being a possibility also I am not circumcised but I take good care to clean it thoroughly when I shower. I also tried cleaning it with a hand soup because I thought if I clean the early as much as possible it would help clear the rash but now it seems my penis is drying up and it just started to itch this morning no weird smells or irregular discharge is coming from my penis.

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Cyclizine Reaction - 9 Weeks Pregnant

I'm 9 weeks pregnant, and today was admitted to hospital with severe morning sickness and dehydration. I was in a&e, and at this point, sick, tired, but generally in good spirits, no anxiety, and to be honest, pleased about being given fluids at last!

I was then given a dose of Cyclizine in my IV, I'm not sure what dose it was. Literally as soon as it went in, I immediately had a very strong urge to vomit, which I managed to fight off. I started to shake uncontrollably, and felt very 'woozy'. The nurse didn't even give me the whole dose, he decided to stop at the point. He then left, and my boyfriend had to call him back in. I went as white as a sheet (according to the boyfriend), was still shaking uncontrollably, the nurse did my obs, and my heart rate was about 150 bpm. I became extremely anxious, with a feeling of impending doom. I was apparently not acting 'normally' for me and not speaking properly. I tried to get up, but my whole body felt extremely heavy.

For me, the whole episode felt to last a long time, but my boyfriend states that it lasted no longer than 10 minutes. The shakes took an hour to wear off completely, and the heaviness, at least 3 hours. This evening (12 hours on), I still feel anxious and 'not quite right'.

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Cyclizine Reaction? Acute Insomnia

I am experiencing acute insomnia. Is this familiar to any other users of this medication?

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Cardiac Arrest As A Cyclizine Reaction

I was in hospital in 2006 with severe illness. I had gotten up to go to the bathroom yet collapsed on the way there. I was given morphine as I was in extreme pain, however, i began feeling very sick, so cyclizine was put straight into my drip. Literally 20 seconds later, i remember feeling as if someone had put their hands round my neck - I couldn't breathe and my heart was racing - this is the last thing i remember. According to my mother and father, I went into cardiac arrest - blacked out, and then was unconscious. At this point, I was dead. I had no pulse and was not breathing. I was given emergency CPR and was thankfully, revived. I remained in hospital for the next week under strict observation. I was 15 at the time. I have a severe allergy to cyclizine, and never again will I go through this ordeal.

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Cyclizine Is A Dangerous Drug Due To It's Reaction

Cyclizine is dangerous and  I will not stop  warning people of the awful reaction to the drug company to own up their responsibility.  I cannot do this alone, I need all your help we have to warn  people of the danger of taking cyclizine.  

Positive feedback on this?

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Cyclizine Reaction :: Very Frightening Experience

The first time i experienced IV cyclizine i was aware of it ascending in my arm and reaching my heart. I had a sense of 'falling' and 'doom'. With this i felt my heart jolt. I asked the nurse to stop the infusion as being in pain was preferable to the sensation i was feeling from the drug.

I was given iv cyclizine again several years later as i had forgotten the earlier experience. As soon as it entered my circulation i soon remembered and was a far more frightening experience. The sensation of falling and imminent doom i now interpret as a 'feeling of dying'. My heart reacted the same and an ECG showed cardiac changes. The sensation stopped immediately as the infusion was abandoned. I now have cyclizine allergy on all my medical notes as i never want the experience again.

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Cyclizine Reaction - Real Bad Dizziness

I started taking just 1.

Then today iv taken 2

I get bad dizziness and wen I mean bad I mean bad.

Any positive feedback on this?

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Cyclizine Reaction :: Thought I Was Dying

Had injection of cyclizine for nausea during recent hospital stay.

Was asked if I was allergic but hadn't had it before.Immediately felt terrible, thought I was dying, heart rate up to 135 BP 200 even temp up to 38

Also felt really sick Treated conservatively over the next 3 or 4 hrs, ecg and frequent bp etc. Dr. said antidote could have caused even more problems. Never want to go through anything like that again. Hope hospital records these allergies and informs drug companies.

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Contraception :: Copper Coil Causing Allergic Reaction?

I had an IUD put in on 2Oct. I have been bleeding excessively(confirmed by doc), cramping almost as bad as my miscarriages, nauseated, drained feeling, achy, sharp shooting pains throughout my uterus and surrounding area. I had an ultrasound done to make sure the IUD is in the right spot and it is.
I have always had sensitive ears and only able to wear silver and 14k or better gold earrings, but lately my ears are reacting even to those now and in a worrying speed.

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Bad Reaction To Cyclizine - Twitching With Dry Mouth And Throat

Was given cyclizine for nausea. I have just had the most frightening two days of my life and I'm still feeling dreadful. I couldn't breathe, my chest felt like I had an elephant sat on it. My heart was constantly racing. Dry mouth throat and nose. Arms and legs twitching. Nausea, dizziness. Very restless and scared.

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Cyclizine Reaction :: Arm Blush Red And Stroke Like Feeling

It was administered intravenously . After less than 10 minutes, he experienced a frightening and vivid brightening of all the veins and capillaries in his arm which then caused the whole arm to blush red.

At the same time, he completely lost his ability to speak. He was unable to call for help or answer any questions when assistance arrived. He was distressed, very anxious and thought he had suffered a stroke.

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Herpes :: Clitoris Inflammed - Hydrocortisone Cream Allergic Reaction?

So recently I have had these bumps they could be ingrown hairs not sure. Had unprotected sex 7 days ago .Today I look at the hood of my clitoris and it was inflamed I'm guessing because I applied hydrocortisone cream on the bumps on my pubic area and I could be having an allergic reaction but then today the skin was peeling off the hood of my clitoris. If I had herpes would Hydrocortisone cream heal the bumps? Because I don't think hydrocortisone would work. The bumps are hard and not in clusters. They don't look like blisters and it does burn when I pee..

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Cyclizine Reaction - Chest Pain, Twitching And Convulsions

I had a stomach operation in April, and on the day I should have left hospital, I felt sick.I was given this drug by an I.V. access in the back of my hand. The nurse hadn't even finished the jab, when I got a horrendous chest pain, followed by the most excruciatingly uncomfortable 4 1/2 hours of my life! My whole body started convulsing, like someone had connected me to 40,000 volts, and it was being sent through my body every 30 seconds to a few minutes at a time. I have a heart problem, and I don't think I should of had the drug, even though I have had prochlorperazine(a similar anti-sickness) drug in the past. I can assure you, this was not just a mere reaction to the drug. Since surfing around the net for some answers to my symptoms, I've found that they were that of a cyclizine overdose, although, I think the dose was possibly correct ! Steer clear of this drug if you haven't had it before,especially if you have heart trouble. This event has scarred me for life,and if anyone comes near me with it again, I'll personally shoot them. Take note, drugs have horrid effects sometimes.

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Cyclizine Reaction / Side Effects - The Drug Should Be Banned

Today my husband was given Cyclizine due to feeling nauseous - within seconds we knew there was something terribly wrong - he started to panic - he kept holding his head saying god, what is happening ??? His blood pressure shot up, the nurses had to try to weaken the effects as quickly as possible using saline down the PIC tube. It was all very shocking and the drug should be banned !

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Cyclizine Reaction - Oculogyric Crisis - Involuntary Facial Movements

I had surgery to remove a kidney stone last month, I was given cyclIzine to take home along with pain meds. After a day of taking the cyclizine tablets all of a sudden I felt really on edge and strange and had gone from being quite sedated from pain meds to breathing unusually. I had involuntary movements in my face and neck. It progressed into difficulties talking, my gp told me to stop taking cyclizine immediately. 2 days later the symptoms were worse so my gp gave me procyclidine to stop the symptoms. The following night they got even worse and apparently it's called oculogyric crisis, felt like I was fitting. Being treated with sedatives now which have really helped, it's a month later now though and I had a series of episodes last night of oculogyric crisis. Has anyone else had similar experiences and how long did your symptoms last?

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Cyclizine Reaction - Patient With Neurological Problems? Yellow Card Report

I have just had heart surgery . And given iv. Cyclizine. I suffer from dystonia. I believe you shouldn't be given it if you have neurological problem?  I had no coordination , trouble talking , walking, just kept seeing circles, drinking gallons.. Notes on record, patient was disorientated, ha what a joke!. I will look at this yellow card. I haven't heard of it.

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Cyclizine Dangerous Reaction :: Anaphylactic Shock And Couldn't Breath Unassisted

I was taken into hospital with severely painful kidneys, and given morphine as pain relief. Unfortunately this gave me terrible nausea so I was given Cyclizine via IV. Within 10 seconds I went into anaphylactic shock and couldn't breath unassisted. I had to be given adrenalin and was on oxygen for a considerable time. For the next two days I couldn't urinate and had to be catheterized. It was a frightening and stressful experience. The attending doctor told me that it was unheard of for anyone to be allergic to this drug, and that my inability to pee was not connected. I am still trying to recover. More research needs to be done. I believe this drug is dangerous.

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