Started sovaldi and ribasphere yesterday and within hours was vomiting diarrhea shaking. Dr. Does not think it's related to meds. But stopped until mon. Will try again in a few days. Has anyone had this reaction. I'm terrified I cannot finish tx.
View 11 RepliesMy wife had a bladder infection (the second within a month) and was prescribed a 7 day course of trimethoprim. On the 7th day (having taken the last tablet) she began vomiting and shaking - within 10 minutes of this starting she become disorientated and lost her memory. She was immediately hospitalised and given a MRI scan of her brain plus various blood and urine tests but all tests proved negative. For 24 hours she suffered from extreme short term memory lose. She could not remember events that had happened just 10 seconds before hand. Very scary. I have found this web site on the second day and am relieved to see she is not alone and that the events she is experiencing are probably related to trimethoprim. 36 hours later she is still bed bound (now back at home) and has a bad headache and hot/cold sweats, neck pain and diarrhoea. Sleep seems to be the best aid but she is finding it difficult to sleep as her brain is a hive of activity trying to reconstruct the lost bits. The only drug she is now willing to take is paracetamol which helps a little. Thankfully her short term memory is now working again. How this drug has obtained a licence is a question that needs to be asked
View 1 RepliesI am 32 weeks pregnant I am vomiting and I have diarrhea all at the same time it is coming out of both ends at the same time should I got to the hospital or not and I know it's not the flu.
View 1 RepliesHow does one take the Sovaldi? On its own at a different time of day or together with the first dose of Ibavyr?
View 3 Repliessomeone wrote on other forum that Sovaldi killed her mother. She is suing the doctor and it's kind of scary reading about it. Have there been many deaths associated with Sovaldi?
View 32 RepliesHas anyone on treatment with any Sovaldi combo experienced ascites?
I have been on Sovaldi and Olysio for 8 weeks now and have noticed quite a bit of fluid just at the top of my ribs, making me look maybe 3 months pregnant. I don't want to say anything to the doctor because I don't want to stop my tx. I know everyone says drink a lot of water, but I am thinking perhaps I have been drinking too much water and the kidneys are suffering with processing it. Also, my breathing is more heavy than it was just a week ago if I go walking. I do new labs in a week so will be able to see if anything is awry, but mostly I'm curious as to whether anyone else has experienced this.
Perhaps it is not even ascites and I've just been eating too much.
Ever since i started taking new prenatals (stillman valley prenatals from walmart ) I've been puking & right after I get the runs . It's just so disgusting and I want to make it stop , any chance that it might be the prenatals ?
View 4 RepliesI m 36 week pregnant. And having diarrhea and vomiting . feeling so uncomfortable. Anyone experiencing same situation ? Any solution ?
View 2 RepliesWoke up today feeling extremely bad. Had bad diarrhea, and was vomiting every liquid I was taking in - I don't know if I specifically had/have the "flu," but the symptoms of diarrhea, vomiting, muscle weakness/aching, etc. seems to point to that conclusion. My reflux issues most likely worsened the ability to keep liquid down, and, as a result, I almost passed out from dehydration. Luckily, I am with my family, and am starting to take liquids down. I have good health insurance, should I need to visit the hospital if things get really bad.
I'm wondering if I should take any special considerations, or what other things you guys might suggest, as this has been pretty brutal on me today.
My Doctors say we have a victory. He says no one after 3 months being negative has relapsed.
We took a lab draw 4 months after the meds stopped am I'm clean. We will do another 6 months from now just to nail it in but he is confident I'm done with HCV.
I was Negative at the 3 months lab draw.
I was GenoType-2. Had it since 2006, treated twice on the interferon and Ribavirin, once for 6-mos and another a year later for a year. Relapsed both times.
We caught mine very early in the antibody stage.
I asked about the ones who relapse and the trend there seems to be obesity.
I wonder if any readers have taken sofosbuvir. What is your experience? Mainly, how did it get financed?
I would love to get rid of my Hep C, but wonder how anyone can afford the new treatment.
I'm a Gt3 and while I'm excited to be on treatment, I also feel slighted almost that I can't take Harvoni. I'm always searching for results from others with the same as me but I don't see much. I have 8 more weeks to go from a 24 week treatment of Ribavirin and Sovaldi.
View 15 RepliesA newly-released study shows that data from trials does not correlate well with data from real life. The statistical study revealed that four times as many patients treating with a Sovaldi regime stopped treatment before finishing than in trials. probably the same discrepancy exists regarding cure/relapse rates and maybe even adverse effects.....
View 69 RepliesI've just started this new combo and I'm finding only a couple comments from others. Has someone actually finished a treatment? If so maybe you could share your outcome? I'm having the official advertised side effects plus sharp groin pain.
View 1 RepliesFor the past 10 years I have had severe digestive issues. If I eat more than twice a day I will spend the majority of my day in the bathroom so I avoid eating especially during work hours. I also have a hard time drinking a lot of fluids and if I drink too much I end up vomiting? I have heartburn almost daily and ironically water seems to make it burn more than most beverages so I really don't drink near as much as I know I should. I have had several upper and lower scopes, colonoscopies, breath test and worked with nutritionist and they all are baffled and tell me nothing is medically wrong with me? I recently feel like im constantly on the verge of getting charlie horses in my legs, have random blurriness in my eyes and I'm just tired. I am broke out of my mind and quite frankly feel hopeless because even if they did find something I can't afford to treat it? I'm frustrated, scared and exhausted. I have no idea what is left that I can do?
View 1 Repliesi'm 18 years old and on the first day of my period i have a terrible cramping, if i don't take nimesulide 100 mg when i feel the first signs (usual painkillers like paracetamol or ibuprofen don't do anything, even in high dosage) then then i get diarrhea and even vomit, and the pain seems almost unbearable. I'm a virgin, if it has any importance. Is there a way to stop this, or will i have to take nimesulide every month? (By the way is that safe to use it that frequently?) Even if i take it, it takes 1-2 hours to have an effect, if i don't take it early enough, then even more.
View 2 RepliesThe past 9 weeks I treated with olysio and sovaldi. They stopped at 9 weeks. The test came back at week 8 still positive. Tx was stopped. Geno 1A, Past biopsies showed stage 1 mild fibrosis. In 2010 they didn't get a good sample but told me it was probably still stage 1, but not sure. Now after an ultrasound that's "suggestive" of cirrhosis I fear after failed tx the progression will bring me down even quicker. Anybody have any GOOD info that olysio/sovaldi speeds up the virus progression? Dr.says no. Have been positive for 50 years. Since 1999 I have lived a very healthy lifestyle. For most of the years I supplemented and took the herbs to keep my liver in as good of shape as I could until a "cure" came along. So much for that idea. I never did the interf/riba. The past couple years for some reason I stopped taking my supplements, (glutathione raising supplies etc) I used to be a member of a group that was alternative oriented, then I stopped that. I did the q80 variance test and it was positive, and so I went ahead with the tx. My question is: Is this new drug coming out only for those who weren't sensitive to the q80? Or is it supposed to take care of tough bugs like mine? Im hopeful I will be eligible for the new tx. Im 68 now. I am starting to experience symptoms, unpleasant symptoms. Good days/bad days. Sorry for rambling but I saw Blue Metals comment about disease progression after failed tx and it kinda spooked me.
View 3 RepliesDoes anyone know what the possibility of relapse is if you are und at 4 weeks post treatment?
View 8 RepliesAs per Dr. I'm having to do the Sovaldi and Ribavirin 6 months this seems a very long time compared to what I've been reading but since I'm closer to needing a transplant I suppose he is wanting to make sure the virus clears and hopefully it does as I was a non-responder to the interferon & ribavirin treatment. From what I've read even if there's just one or two whatever they call the virus that's left in your system it can still mutate and go from there. So far I'm only have very bad nausea and headaches at times. First labs Jan 8th....here we go!
View 5 RepliesJust completed 12 weeks sovaldi , Peg and CoPeg ......awaiting blood work results to see if I cleared the Hep C 3 Virus . While I tolerated these drugs fairly well , I am concerned that in the 12 weeks of treatment the liver enzymes which are 150 to 200 respectively , never went back to normal. It seems that my situation may be an anomaly.
View 1 RepliesTreated for HCV Genotype-2 with Sovaldi & Ribavirin for 12 weeks.
Came up undetected half way and drawn full labs today to be read 6/6/14 to me on my follow up.
The proof in the pudding will be for Labs drawn in 1/15.
My sides were mostly nausea but frequent water and making my meals smaller and more frequent all but eliminated that. Three regular meals a day seemed to leave my stomach unprotected in-between. So smaller and more often did the trick.
The Sovaldi seemed to make me hyper. I noticed an hour or so after taking it I seemed to have lots of energy.
Periods of general yuck feeling would come and go, and in different strengths.
Sometimes keeping busy helped and sometimes nothing but the couch would give me comfort.
I took the Riba in the AM, the Sovaldi mid day and the Riba again in the PM.
Its been a long row to hoe over 9 years. Two stints of Riba & Interferons, 12 and 48 week terms both relapsing, then on the interferons only @ half dose to maintain while waiting for something new.
Then as a result of all this diabetes and neuropathy set in causing the maintaining regimen to be discontinued.
I don't drink or smoke, I did it all as correctly as possible.