Lupus :: Anti-dsDNA And Anti-smith?


Mar 24, 2015

Are these anti-bodies found in people that do not have lupus? I have both, but the numbers are very low, so they're not flagged. I've seen in a number of places online that anti-dsDNA and anti-sm are pretty exclusive to Lupus.

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Lupus :: Positive ANA Test And Anti-dsDNA But No Symptoms?

The short version of my story is I went to a fertility doctor after having trouble conceiving my 2nd child and having a miscarriage..the dr ran a ton of blood work and I came up with with a positive abnormal ANA (no numbers listed) and a positive high anti dsdna at 38..I think it said over 9 was considered positive. I have zero symptoms of lupus and am now scared to death I have lupus. Could this mean anything else??I have an appointment with a rheumatologist next week but this is the hardest week while I wait. I spoke to a friend's aunt who is a rheumatologist and she thinks the positive anti dna is rare in people in my age to be false (i'm 32) and thinks I may be developing lupus. I am assuming the rheumatologist will re-run all these blood tests and add some of their own but could this be something else? or nothing at all?

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Lupus :: Positive ANA And Positive Anti-dsdna

So I have been sick with a mystery illness for the last year or so. I've seen every specialist, and the first thing they looked for was a malignancy, but there seems to be nothing. Then I saw a rheumatologist and she sent me for blood tests that came back with a positive ANA and positive anti ds-dna. From what I've read, positive anti-dsdna is VERY specific to Lupus. I never thought I had Lupus because my symptoms weren't specific to it, but after ruling almost everything else out, I'm thinking more and more that Lupus could be it. Because my symptoms weren't specific enough, my rheumatologist told me she wanted to see me again in 3 months to see if there were any progressions. I'm really becoming more certain that it has to be Lupus with these positive tests, and I'm worried that I won't be able to get a diagnosis for a long time to come.

Some of my symptoms include:
Extreme fatigue
Constant low grade fever
Neck discomfort
Headaches
Random pains in fingers and knees (not constant, every once in a while)
Chest pain when breathing deeply
A lot of memory problems
Thinning hair
Can barely work out or walk at the same speed as most people

What do you think I should do next in order to speed up finding a diagnosis? How do I make it clear to my rheumatologist that I feel like this is becoming more and more urgent?

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Lupus :: Positive ANA 1:40 With Positive Anti-dsDNA

2 years ago it was ANA 1:80 and the anti-dsDNA was 10, now it's ANA 1:40 with anti-dsDNA 22. So which is worse ?

2 years ago they said it's borderline and if I don't have symptoms, let's wait, they didn't dx. me with lupus.

I had ( and still have ) unexplained hip pain ( comes and goes ), headaches and lightheadedness ( had them before, but usually around periods ), but 2 months ago they become very bothersome and almost constant. My vitamin D is 25 ( should be 30-70 ) and vitamin b12 is 244 ( should be 200-900 ) my dr.said is still kind a low
.
Are these lupus symptoms at all ?

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My grandmother is 53 years old and has arthritis. She takes cataflam against pain and inflammation. Some time ago she started telling us that her tablets are missing. She thinks someone is taking them. I have a younger brother who is a teenager. When I asked him if he knows anything about grandma missing medicine, he yelled at me, slammed the door and went out with his friends. Is it possible that he is taking Cataflam? I mean, is it possible to get a high of cataflam?

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Autoimmune Disorders :: Positive ANA And Anti-SSA/Ro

I was diagnosed with fibromyalgia years ago due to constant and sometimes debilitating muscle and joint pain. I am seeing a new PCP and she ordered some blood tests. The first was just a general screening but my c-reactive protein came back as elevated (also my platelets) so the doc ordered an ANA with reflex if positive. ANA came back positive (no titer information - it was just a positive/negative test I guess) and anti-SSA came back at 8.0 (negative range is 0.0 to 0.9). But RA factor, anti-centromere B antibodies, anti-dna (ds) qn, anti-jo-1, anti chromatin, anti scleroderma-70, rnp, anti-SSB, and smith antibodies are all normal.

Besides my muscle and joint pain I have had periods of alopecia (losing quarter to half-dollar sized patches of hair on my head), full-body rashes during especially hot times, asthma, and suspected endometriosis (currently controlled by depo-provera). I also used to never get sunburnt but my face especially gets really red now if I am in the sun for more than a little while. I have darker skin so its sometimes hard to see but lately my cheeks and nose seem constantly flushed.

All of these symptoms have been spaced out and gradual so I never thought anything of each individual symptom. The alcopecia was blamed on "stress" when I went to the doctor for it. The rashes I blamed on a simple "heat rash". My pain was diagnosed at first as carpal tunnel and then as fibromyalgia. But now with the ANA and anti-SSA tests I am thinking it all may be related. But I don't know and my doctor is out of town, and although I know she will refer me to a rheumatologist now as we have talked about that, who knows when I will actually be able to see the rheumatologist. So any thoughts would be greatly appreciated. I am thinking maybe SLE (lupus) but with only that one anti-SSA and none of the others I don't know. Also I do have flares 2-3 times a month where my pain gets much worse but it constantly hurts and aches the rest of the time regardless, which doesn't seem like typical lupus. Oh and I also had severe fatigue until my doc put me on Savella which helped with the fatigue but not the pain. So now I am on gabapentin also but it doesn't seem to help too much either.

I would do almost anything just to be pain-free for even just a day. I am hoping with the ANA results now the doctors will not only maybe be better able to treat me but also will take my pain seriously.

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I’m bit afraid that I might go into withdrawal from Xanax, so I’m wondering would it be OK if I continued to take Xanax for at least a while together with Lorazepam?

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Searching online I’ve stumbled upon information about Rozerem that should work precisely to help you fall asleep, and I’m definitely going to talk about this medication at my next psych appointment. What worries me though is - is it safe to use both Xanax and Rozerem at the same time?

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I’ve been reading a bit about this and came across info that Xanax is more effective than Lorazepam in fighting anxiety attacks, is this true?

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Now i’m thinking to see my doctor to prescribe me some sleep aid and I was wondering what are your experiences with Valium and Xanax - which one works better as a sleep aid?

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I need both my hips replaced, does anyone know if it helps with hip pain? 

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