Neurological Disorders :: Periodic Muscle Weakness
Mar 25, 2015
3 years ago i developed muscle weakness in my legs that meant i could not take a normal step or raise my leg off the bed,after about 2 weeks this started affecting my arms as well meaning i could not lift my arms above my head, the weakness is periodic and last for anything from 5 mins to 6 days. it varies in strength, when its at its worst i cannot walk at all. the longest i have been symptom free is 5 months. there is no pain involved at all. i have seen various neurologists and had MRIs and EMGs, my reflexes remain intact, i have also seen a psychiatrist who said i need to see a neurologist.
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For the past 3 months I have had progressive symptoms of numbness and muscle weakness all over my body. It all started with sciatic pain that radiated down my legs and prevented me from sleeping. That went away. Then about a week later my hands and feet started to have a pins and needles and loss of sensation feeling. a week after that my neck became very stiff and sore. After that my muscles became very tight and inflexible. After that I developed a tremor in my hands when I go to do something requiring hand focus like writing pointing or typing. after that the loss of sensation in my feet progressed up my leg and now I have leg weakness which prevents me from running and jumping and my balance is very unsteady. lasty my face muscles are weak I cant fully smile or use my muscles and I cant raise my eyebrows at all Every week or so since i've had a new symptom. and I am very alarmed at this point . I don't have any diseases or conditions now im 23 in good shape work out.
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Although I try to be as active as possible my muscles are making life for me difficult, as for years they have been wasting, causing pain and tiredness. All other symptoms point to Fibromyalgia, which I believe doesn't cause muscle wasting.....also have Osteoarthritis. My muscle problems started in my mid. 30s.....am now 63 and is much worse. Recent blood tests show normal muscles values....but something must be wrong as my energy level is very low. Has anyone been /going through the same??
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I am a 29 year old female and I was diagnosed with Hashimoto's Thyroiditis at the start of the year. I have been having problems with my right eyelid in that over the course of the day it progressively becomes droopy and the only thing that relieves it is when I close it. When it becomes droopy it makes my eye feel like there's something in it and I end up rubbing it. It's only when I look in the mirror that it's droopy.
In January my endocrinologist ran an autoimmune profile (but not for every single antibody) and rheumatoid factor and these are the results of it:
Rheumatoid Factor - 9IU/mL (<20 negative)
HEP2 - Positive
Type - Speckled
Anti-DSDNA - 7IU/mL (<30 negative)
(Positive antinuclear antibodies but no significant disease association found)
ENA screen - Negative
Autoimmune profile
Antinuclear Abs - Positive
Anti-Smooth muscle Abs - Negative
Anti-Parietal Abs - Negative
Anti-Mitochondrial Abs - Negative
Anti-LKM Abs - Negative
Anti-Thyroid Peroxidase Abs (Anti-TPO) - 141 kIU/L (<34 negative)
I am posting here because I have a suspicion that I have Myasthenia Gravis. Not only have I got the problem with my eyelid but I tried to follow some physical tests for muscle weakness such as holding my arms out straight in front of me and deep knee bends.The results of these home tests I did:
Holding out arms stretched in front for 60 seconds - pain in both arms when it came up to the 60 seconds and left arm dropped slightly
10 deep knee bends - did all 10 knee bends but the last 3 made my legs feel weak and shaky
5 sit-ups (sitting from lying down) - could only manage 4 sit-ups
I have an appointment with my GP on Friday and since this has now appeared I'd like to mention my concerns to them.
My main concerns are :
Wouldn't my endocrinologist have tested me for Myasthenia Gravis if it's an autoimmune condition? If so what antibodies would she have tested and would any of the ones I had tested have shown I have Myasthenia Gravis?
Who do I need to request to see to get a confirmed diagnosis?
If it is indeed Myasthenia Gravis would it be because my current autoimmune condition made it worse? I have read that this is possible and I became very hypothyroid yesterday as I had very bad Reynaud's flares when out and about.
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for the past week I had severe joint pain and weakness, muscle weakness, bone pain in extremities ( had a blood test for lupus and RA[ no family history of either] Starting to get a bit better as long as I rest. recently sexually active with one person, now I just noticed feeling swollen like I was getting a UTI ( hurt when I urinate), but noticed it hurt in my vagina not urethra, checked and there are 4 small red bumps in my right labia minora and 1 in my left labia minora-odorless, feels inflamed and hurts now. Is this related to possible lupus or separate problem? I feel exhausted and run down.
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When in bed at night I struggle to turn over or move as I feel so stiff and sore. Once out of bed and moving I am much better. I initially find it hard to become upright after sitting for any length of time. About 2 years ago my daughter noticed my right calf was much smaller than my left one. I cannot raise my self onto my toes on my right leg due to loss of muscle/strength in the affected leg.
I have had blood tests, nerve stimulation tests and a muscle biopsy. My CK level from my blood tests was slightly raised, my nerve study tests were abnormal and my biopsy only showed minimal change.
I now cannot raise my arms above shoulder level to the front and if I walk at a quicker pace my lower back feels like I have no support and I get pain around my lumbar region.
I go spinning 4/5 times a week and cope with this very well. It's as though once I'm warmed up my stiffness diminishes. I am 51 and have only one period every 3/4 months , I have been to the dr's re the menopause but have been told all my blood tests are normal.
i have been referred to a neurosurgeon and neurologist with ? A form of muscular dystrophy but now my muscle biopsy result has not shown the expected result.
i struggle going up and down stairs often. I feel so fed up with my inability to do what I want to do as I have always been an active person. I have put weight on and cannot motivate myself to control my diet.
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Back when I was 15 I started fainting, it didn't happen often but it always seemed to be in the morning after a cigarette. I would feel myself going, my fingers would go all tingly, and it would work all the way up to my head and my vision would go blurry and then i would fall. Over the next few years it was happening about once a year but this time it seemed to be caused by severe period pains - it happened at work once and an ambulance was called and apparently everything was fine with me. When it was period pain related i had more the sweats that would start right before and my hearing would go all tinny.
I am now nearly 25 and like most young adults I often go out drinking with my friends. It now seems these 'faints' are happening the morning after the night before type thing. It's happened twice in the past 3 months, once at home and one last week on a bus on the way to work.
Once again, i get the tinny hearing, tunnel/blurry vision, excessive sweating and heavy breathing and then i just go, but on the past 2 occasions, i've woken up almost having a fit - but its only my head that is shaking from side to side and i can't control it for a good 30 seconds and can't figure out where i am and am so confused... On top of this, on both occasions (unlike the previous 10 years) i have lost bladder control.
As i was on the bus for the most recent one i was roughly able to work out how long i was out for judging from memory of where i lost consciousness to where i regained it and it must've been 1-2 minutes. I don't think i could've been 'fitting' that bad on the bus as my head bust rested on the chair in front and i woke up smacking it with my head (sounds funny now, terrifying at the time!) so must've just looked like a weirdo on the bus. When it happened in my kitchen, i felt myself going so sat down but woke up with my head smacking against my cupboard door.
It's a horrible feeling and i know by the sounds of it alcohol is the main cause but i have many friends that drink a lot more than me and they certainly don't have any of this.
It's worth noting that i have been on Citalopram (10mg) since August 2014 -although i don't think the dose is strong enough to make any change to my mood let alone any side effects. I'm currently undergoing tests for a lump found in my breast which has been ruled out of being a cyst so awaiting results until beginning of May.
Is this anything to be worried about do you think? I've resisted going to the dr's as when it's happened before and paramedics were called and they said it was nothing and when i fainted in oct 2013 i went to A&E and he said i had extreme low blood pressure and i just got up too quick... but other than that, all blood tests and BP checks i've had in the past 2 years have said im fit as a fiddle basically.
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my top half of my leg has swollen it feels like pins and needles and it feels like water is running down my leg it is very painful to touch very lightly.
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for a few days candesartan was helpful then the side effects set in. especially dizziness and arm muscle pain and elbow joint anyone else have this problem
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I've been having muscle weakness and burning in my arms and legs and back for about 8 months now and am so afraid that I have als or ms. I was wondering how long does it take for als and ms to manifest ? This is causing me great stress and depression.
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The last 2 months I've had tightness in my left buttock while on Prednisone. For the first while I could walk if off but for the last month it is constantly there but only when I walk, and sometimes shifts to the left leg's inner thigh, the result being I find I'm sort of limping. Has anyone had something like this? It could be a disc in the lower back pressing on a nerve affecting the muscles in the buttock and thigh, or maybe it's just muscle weakness resulting from the Prednisone. I'm in a quandary how to tackle it, see a physio, chiro, massage therapist. I've found that since I've had PMR 2 years ago anyone working with their hands on me greatly aggravates things so I'm unsure where to turn.
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I was diagnosed about 4 months ago with Hashimoto's. I'm on 75 mcg of Unithroid. I've started having extreme joint pain and my hands are always swollen. Some days it's a chore to walk up the stairs at work. The only time I feel really good is in the evening about 7pm. Any suggestions on what this could be? Who do I see for my joints to rule out other autoimmune disorders?
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Help! In 2001 I had a thyroidectomy. Immediately, my blood pressure, (which had always been remarkably low), shot through the ceiling and I've been on BP meds ever since. But I digress...
I was always super active. I skied, ran, kite boarded, hiked, biked... all a healthy and important part of my life. I even had booked a trip to climb Kilimanjaro for my 60th birthday in 2010 when I came down with Swine Flu, followed by a couple bouts of pneumonia. When I recovered, I tried to go back to skiing about three months later and found that I had lost muscle strength! I couldn't make turns (and that's a bad thing...) I got weaker and weaker. My doc had no clue. We checked heart, lungs. I was at low end of thyroid and adrenal levels, but "not a problem", I'm told. I'm not a drama person at all, but I really began to believe I was dying because I was getting weaker and felt like my energy was draining away.
At wit's end, I went (for the first time) to a brilliant naturopath who drastically improved my already good died and put my on Chinese meds. It took about three months, but I eventually stopped getting weaker and became stable. That was HUGE! Since, however, I've remained pretty stable and we keep trying other things but nothing has put me even close to where I was.
The best guess is that its related to thyroid or adrenal function. I dunno...
I can now make between 6-10 stairs before I have to stop for a few seconds to regroup. I can swim very short distances but never alone because when I run out of energy, its GONE and I have absolutely nothing left. This has drastically impacted my life and I want to be strong again!
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I was diagnosed as hyperthyroid about five months ago. I am so much better now however the tremor in my hands and the muscle weakness in my arms and thighs doesn't seem to have subsided (or even lessened) at all like the rest of the symptoms. I am really worried that these are going to be permanent problems. Has anyone else had tremors and muscle weakness from this condition, and did it eventually go away or should I be preparing for this to be a lifetime issue? If yours did go away, how long did it take and did you need to take any particular supplements or do any particular exercises to help?
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I've been worried sick about my health condition these days I can't function well in school. My arms and legs have been feeling weak and have been getting short but sharp cramps. They would also feel numb sometimes along with a tingling feeling. I also seldom feel some muscle twitching which are not painful.
This happened a day after a very mild workout. Since then I haven't exercised due to the weakness of both my arms and legs.
The results I've been getting from the internet had made it difficult for me to sleep and go out. I am terrified this could be ALS. Is there any chance, even a slight one, that this could not be something serious? I am almost convinced that this is ALS but I still have a small dash of hope that it isn't.
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I'm feeling alone and not sure who to turn to ask and feeling like no one quite understands. My main concern is that sometimes when I get muscle weakness and feel tired, I start craving to eat and I can't stop myself even if I have already eaten well. Yesterday evening was the perfect example, Having eaten a full meal with vegetables, rice, noodles and chicken, I then followed it with a bowl of fruit with yoghurt. Very healthy, should have been enough. I then had a bowl of cereal with milk, handful after handful of cereal from the cupboard and other food I could lay my hands on. I managed to stop myself when the feeling of wanting to eat spoonfuls of sugar and golden syrup and sweets and chocolate out of the cupboard. I think felt overwhelming tiredness and ended up lying down unable to move all evening eventually falling asleep.
Today I am so shattered, I feel weak, tearful and tired and I have just been eating and eating all morning. I can't cope.
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I have been advised to take Lipitor but experienced muscle soreness and weakness. My doctor then reduced dosage, but it still had the same effect. He then recommended I take a low dosage two times a week as long as I could tolerate it. Will such a low dosage have any positive effect on reducing bad cholesterol?
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My 30 year old daughter has been doing this for the last several years. She can resist doing it for a while, but typically snorts every 45 seconds or so when she doesn't feel a need to limit it. It's loud and unpleasant. She says it feels like she can't breathe so she is actually snorting in her throat more than her nose. She feels like her throat is tight and not letting in enough air. I know it's bothersome for her, but it is maddening for those she lives with.
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I've been on nortriptyline for daily headache prevention for over 20 years. Has done an excellent job in headache prevention and just helping me feel normal. Just in the last year as I'm at the door of menopause, I've been experiencing pain and tightness in my hips, perineum, and sit-bones. Also a lot of stiffness and weakness in surrounding muscles. I attributed it to my sit-down job, but I now have a standing desk and am still experiencing a lot of pain. Wondering if nortriptyline is the cause of it, and am thinking of weaning of it. Has anyone else experienced this kind of pain as side affects of nortriptyline.
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I was wondering if anyone has experienced muscle weakness (that never goes away) with thyroid medications? I have had this with Levoxyl (12.5 mcg.) and with Armour Thyroid (15mg.) as well as all other thyroid medications (even at the lowest dose). Perhaps I don't really need thyroid meds at this point (my TSH was 5.8 when off of thyroid meds). I saw somewhere that weakness (especially in the arms and thighs) is an indicator of too much thyroid hormone.
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Three weeks ago I noticed my daughter (age 38) could not remember anything from 10 or 15 minutes and kept asking the same questions - She seemed confused. I took her to the hospital and they began running test. After 2 days she was having difficulty standing so I had to help her stand and then she could walk - after 4 days she could not stand or walk at all. Her legs and arms both have some numbness, burning sensations, and pain. The MRI scan shows no issues - they have run MRI, CatScan, EEG, EMG, Muscle Biopsy, Spinal Tap, all sorts of blood work and after three weeks have found nothing except some vitamin deficiency. She still cannot walk and has confusion and short term memory - Has anyone heard of anything like this. Is it possible that is vitamin deficiency?
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