Pizotifen Destroyed Our Marriage


Jan 15, 2009

I am amazed and horrified to find that this drug is still being handed out to people with out proper supervision and advice. My husband was prescribed the drug a few years ago by his G.P. as his migraines had become more frequent, due to stress at work etc. He changed from someone who had little trouble getting up for work to a groggy, bleary eyed creature. Over the next 12 months he became increasingly belligerent, aggressive and unbearable to be around. He also experienced almost permanent numbness down his left side, like a mini stroke. I was just at the point of leaving this dark, brooding monster who was the antithesis of the funny, loving, intelligent man I married, when it occurred to me that this personality shift had taken place since he'd been taking this drug. Having picked one of his better moments to talk about this, he decided to stop taking the drug to see what happened. Within 24 hours my beloved husband was back. I got hold of the drugs and the information leaflet contained within it and realised that almost every side effect listed applied to my husband. Having been back to the G.P. together to discuss the effect this dreadful stuff had, she thought he should still take it and take anti-depressants as well, no thank you.

I had always suspected that many of his migraines were triggered by low blood sugar, no breakfast, missing lunch etc. and now he has adopted regular eating patterns in combination with the herbal remedy Feverfew he has only had two migraines in the last year. We were told subsequently by yet another G.P. at the practice that Pizotifen is only supposed to be prescribed for people with debilitating serotonin triggered migraines, that it is a drug of last resort for people who cannot function on a daily basis due to persistent attacks. He also pointed out that not only should it never been given to someone with the level and type of migraine he had, but also as he drives to work every day he should never have been prescribed this drug as it renders you unfit to drive or operate machinery, which the original G.P. should have known but never mentioned. . Thank goodness he didn't come to harm or cause any!!! We recently came across a couple pulling their hair out over their migraine suffering teenage son. He has recently been prescribed Pizotifen and has become so awful that they were considering throwing him out. We couldn't believe that it was happening to someone else and hence I searched out this site. It is a serotonin inhibitor. So unless you have migraines every day and you can't have any kind of life because of them find another treatment. Believe me when I say don't take this drug, not if you love your family.

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I have had migraines since i was 12 (I'm almost 28 now) and over the years they have become increasingly frequent. It got to the stage where i was having 4-5 severe ones a week. I'm a medical student so this was REALLY getting in the way of life and i just used to wander round in a painkiller induced daze or be forced to collapse in bed.

A few weeks ago I came to the end of my tether. despite being on beta blockers and antidepressants and armed with seriously strong painkillers and all sorts of things like sumatriptan i was still completely incapacitated with a 4 day migraine. So i took the plunge and tried the pizotifen 1.5mg given by by GP.

Three days went by with no migraine... then a small migraine then another 4 day whopper probably more severe than before which knocked me out cold for the whole weekend and beyond. I've been on the pizotifen for 2 weeks now and low and behold today - another migraine.

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1) Neither of our families live in this country, and because of isolation I have no friends. Although I can stay in a hotel for a while if need be. (I also know that shelters are available for domestic violence)

2) I will be the first one in both our families who is getting divorced. I'll have to explain to all these people, who probably never understand me, why I'm leaving. Because he didn't do anything wrong and I'm the bad one. I accept that, no big deal anymore, but it's hard to explain it to people.

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