Liver :: Daclatasvir Or Sovaldi Lupus Erythematosus Patients?
Oct 26, 2015
One of my friend has Lupus Erythematosus and needs a liver transplant, but during the blood transfusion, she got HCV. She wants to take daclatasvir or sovaldi(sofosbuvir) for curing HCV, but is worried that daclatasvir or sovaldi(sofosbuvir) would have side effect that is bad for Lupus Erythematosus. So I wonder if Lupus Erythematosus patients take daclatasvir or Sovaldi(sofosbuvir) for curing HCV? Were there any successful or failure previous examples?
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i had intercourse with my girlfriend. she's a SLE patient and v had protected sex. but it got torn and later i had to give her unwanted 72 !! will this effect her health in any way and is this SO contagious that i will also be affected??
and that night she complain of a bit bleeding!!! is this any way normal?
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The past 9 weeks I treated with olysio and sovaldi. They stopped at 9 weeks. The test came back at week 8 still positive. Tx was stopped. Geno 1A, Past biopsies showed stage 1 mild fibrosis. In 2010 they didn't get a good sample but told me it was probably still stage 1, but not sure. Now after an ultrasound that's "suggestive" of cirrhosis I fear after failed tx the progression will bring me down even quicker. Anybody have any GOOD info that olysio/sovaldi speeds up the virus progression? Dr.says no. Have been positive for 50 years. Since 1999 I have lived a very healthy lifestyle. For most of the years I supplemented and took the herbs to keep my liver in as good of shape as I could until a "cure" came along. So much for that idea. I never did the interf/riba. The past couple years for some reason I stopped taking my supplements, (glutathione raising supplies etc) I used to be a member of a group that was alternative oriented, then I stopped that. I did the q80 variance test and it was positive, and so I went ahead with the tx. My question is: Is this new drug coming out only for those who weren't sensitive to the q80? Or is it supposed to take care of tough bugs like mine? Im hopeful I will be eligible for the new tx. Im 68 now. I am starting to experience symptoms, unpleasant symptoms. Good days/bad days. Sorry for rambling but I saw Blue Metals comment about disease progression after failed tx and it kinda spooked me.
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Has anyone heard any comments made about A-Fib patients not able to treat?
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I am waiting for a scan and not trying to worry, there is a milk diet designed for gastric patients to clean and shrink the liver before surgery, it also helps to lose weight, thank you for you're replays and you're kinds words, I wish the best for all who are waiting for results.
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I just need to ask that my father was on sovaldi treatment for 4 days when his (serum) creatinine level shot up to 2.53 which later came down to 1.96 and now at 1.43. He has no renal impairment and his kidney ultrasound and detailed urine report is perfectly normal. He is cirrhotic (Hep-c) at stage 2 according to doc (hep-c) which stopped the sovaldi + ribavirin treatment to save his kidneys. However during the period he was also on diuretics (furosemide) occasionally. His nephrologist says that it is safe to continue sovaldi treatment but the other doc gave a red flag (I have yet to have a discussion with the nephrologist). So I am asking that is it possible that creatinine levels change because of sovaldi or do i need to the change my doc? Also he has edema occasionally. He also has acid reflux.
Age: 58 Sex: M Height: 5'10" Duration: a year (stopped sovaldi: a month) Location: Pakistan Medical Issues: Hep-C, 2nd Stage cirrhosis, acid reflux, depression, anemia Medications: Furosemide (Depending on edema) Rabeprazole (Twice daily half and hour before food) Folic Acid Vitamin-D and Calcium
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I've had odd symptoms for many stinging pains, muscle twitching rashes, pancreatitis that is chronic but clear via scans.
Well, almost 3 weeks ago, a large red mark appeared on left breast. I've been going back and forth to doctor as I've wanted to rule out inflammatory breast cancer-it presents with redness etc but no lesions, hard to diagnose. Today when I went back, the doctor felt nodes under my armpit, confirmed during ultrasound, but said they looked benign and small. He said actually it could pop up from autoimmune. He did admit it was odd. It was on the same side as affected breast and not the other. I'm going to get an MRI of my breast as IBC doesn't show on mammogram or ultrasound often.
I've had swollen nodes in the past. I noticed a few times on my jaw line.
I haven't been diagnosed with lupus, tests many years ago were totally clear as were vasculitits tests. But curious if anyone has had nodes on one part of the body pop up. Im praying its not IBC. I'd much rather it be something else. IBC is the most aggressive form of BC and spreads in a matter of weeks, so grasping for other explanations
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I have just found out that my father who has finished his 12 weeks treatment (Sofosbuvir + Daclatasvir) about a month ago has had the virus relapse. It was undetectable in all previous tests, but the recent test showed it. I was wondering if anyone can point me to the right sources, perhaps specialists and experts we could contact as in Poland (where we live) there doesn't seem to be enough information. We are not sure what to do next... He has had this horrible virus for more than 10 years, we were so happy to have cured it! But refuse to lose hope and want to keep fighting!
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My mother is a 65 year old female, 136 lbs, and on peritoneal dialysis for 3 years due to End Stage Renal Disease. Last week, she began experiencing severe abdominal pain that was a burning/gnawing pain. She went to the hospital and a CT Abdomen was taken without contrast. All was normal.
Over the next four (4) days, the pain persisted, particularly during dialysis exchanges at home. She returned to the hospital who admitted her. Another CT Abdomen was taken at this time which showed "nodular contour on the liver", free air in transverse colon which appeared to be dilated. She was also constipated for several days during this period. The CT impression suggested clinical evaluation for chronic liver disease.
A standard liver panel was taken and all results were normal. Nothing even close to elevated. She has never had a history of any liver issues and never had anything show on a CT for liver. After a day in the hospital, all stomach pain disappeared, she was able to use the restroom, and all stool samples/GI tests were normal without blood. She is naturally anemic due to ESRD with low iron/protein. Her last ANA/autoimmune panel was in December, all clear. No history of any hepatitis.
An Ultrasound Right Upper Quadrant was performed and the impression was no biliary obstruction, moderate ascites (tends to be normal due to peritoneal dialysis fluid), and "heterogeneous liver." The impression suggested referral for cirrhosis evaluation.
She began taking Hydralazine (25mg/3 times daily) in the last 3-4 months. She also takes a host of other blood pressure medicines.
QUESTION: She is currently awaiting a kidney transplant and very worried about this. A blood test will be taken in a couple weeks by a specialist that is supposed to diagnose Cirrhosis. Given this presentation alone, what other causes could explain this imaging results? Should we fear the worst?
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I had an abdominal ultrasound done for some abdominal pain and it was noted in the report as an impression that I had an echogenic appearing liver (such as non alcoholic fatty liver). My doctor at that time didn't tell me and just said my report was normal. When I went in for my Colonoscopy that was unrelated, it was mentioned again and when I did some research I realized what fatty liver actually was. I switched doctors.
My new doctor is considering giving me a CT scan but is checking with the GI department to see if they think its needed, etc. etc. But that there is no treatment for it besides diet modification.
Here's the thing. I don't have any of the risk factors. I am not overweight. I'm actually underweight slightly (BMI is 18, I weigh 110 lbs). I don't drink any alcohol, never did. And I don't have diabetes or hepatitis. The only thing I could do and what I have been doing is change my diet. I stopped eating processed foods, watched my sugar/carbs, and eat more vegetables than I ever have.
I'm a very anxious person and I'm not sure I want to know what the scan says. If it's worse than what I thought, I'm going to be so upset and stressed out. And I can't treat it anyway. It's not like they can give me a medication and make it go away. I think knowing the extent of it will just cause me mental anguish and I'm already stressed out about it as is.
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My Cholesterol was 7.8 and I was put on Statins 3 years ago. Because they gave me pains in my legs and other areas I stopped them.
A year ago my Cholesterol was still high and I had changed doctors and was prescribed Atorvastatin 10 mg after 2 months my doctor sent me for blood tests and in a phone call when I was at work he told me that Atorvastatin had caused Liver damage. He said I should stop taking the tablets immediately, pity this advice was not put on my notes so that when I phoned for my blood results a week earlier the receptionist could inform me to stop Atorvastatin. She just said Doctor will be in touch via phone call next week
He referred me to a Liver Specialist.
I went to see Liver Specialist after having Liver Ultrasound. Fatty liver was diagnosed and Liver Specialist promptly put me back on Atorvastatin claiming this would help my fatty liver. I couldn't believe it but what could I do?
Local GP had advised me to have bloods done again after being on tablets for 2 months. When my results came back the Locum doctor I saw said "whoa your Liver is not happy" STOP the tablets and have a blood test in 2 weeks.
2 weeks later Liver levels are coming down so thats a good direction. Dilemma is I have to see my Liver Consultant 16 June 2015. Wish me luck!
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this isn't about me but is about my girlfriend who is about to have gastric sleeve surgery.
She is a 40 year old women that has had a full hysterectomy and has type 2 diabetes. she has had a history of thyroid and weight issues. she is 5,7 weighs 225 LBS. she has an enlarged fatty liver of 27cm and the Doctor said that she needs "emergent" gastric sleeve surgery to bring down her enlarged liver. this was claimed on this past thursday. I have been looking high and low for documentation and statistics on using the surgery for reducing fatty livers but can't find any information. Does this sound right? has there been a history of using this procedure for such cases, I'm worried and scared for her.
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Been feeling lightheaded and brain foggy and a bit sick recently with some stomach grumbling and pain. Went to the doctors who did repeat blood tests over the course of 8 weeks and have said my enzymes are slightly up which could be the result of mild fatty liver. My question is does this sound related? He's also just tested me for celiac, but told me in the beginning that I could be fighting a virus. I'm worried that the 3 diagnoses he's given are so different I don't know what to believe, also does this mean I should be less worried about the tests because they are low enough to be anything?
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I've recently had 2 LFT that both showed raised enzymes, I've had a scan and it shows I have gallstones, however I am currently undergoing investigation into whether I have Reactive Hypoglycaemia, my question is that if I do have RH, would this cause my liver enzymes to elevate?
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IiIt was picked up by chance thaI have fatty liver, could have had this for years without knowing about it, how do I find out how much damage has been done already if any? My GP does not seem too concerned about it, all my LFT have come back normal so what can I do about it apart from lifestyle change which I'm doing already?
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What is the effect of tadalafil in diabetic patients..
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Hello my mother has diabetes and she is trying to Control it, I was wondering what she is allowed to eat? cereals or any other things like that. I have searched online but unable to find something that she can actually eat. I know she's not allowed to have carbohydrates but I can't find things without it, I think 50/50 bread and brown paste are allowed but she can't live on this diet forever.
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I'm looking for advice. My 60 year old father (who has had HCV for more than 10 years; previously treated with Interferon but bad side effects) finished his 12 week Sofosbuvir+Daclatasvir (considered same as Harvoni) treatment a month ago. Already first tests after 2 weeks showed virus was Undetected, but yesterday he received his most recent results and he has a relapse of the virus. He is genotype 1, fibroscan result 4 (close to final stage). He is based in Poland and I'm not sure if our doctors are fully informed of the new generation medications and HCV itself.
Is anyone able to give us any advice? We are pretty desperate and my dad is just so depressed as he thought he finally got rid of the virus (he got infected while on an operation in a public hospital) and now it is back...
Are there any specialists that you are aware of I could possibly get in contact with?
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I've recently been diagnosed with Chiari Malformation type 1 and after reading up on the condition I found that lots of people with the condition either already have or develop syringomyelia. Does anyone know how likely it is that this will develop? Also, does anyone know if the symptoms will continue to worsen over time or will they improve now I'm on medication?
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I've suffered with chronic pain in groin area for over 2years now after a few tests and Mri exam my specialist Dr Chawla told me there's no cure for Neuropathy besides help with medication and pain clinic. None of the painkillers have worked, bad time with side effects! I recently had Acupuncture with Gp only for the pain to spread all over body.
I have had no help and as single parent to 2 children this puts a strain on my depression. I don't want this to take over my life.
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Just before christmas I received a letter from my hospital saying “ recent blood tests show a slightly abnormal liver function and the scan revealed cirrhosis. It is absolutely crucial that you consider urgently reducing your alcohol intake to avoid further liver damage. I would be grateful if you could see your gp to discuss this further.”
Immediately I phoned my gp and couldn’t get an appointment for 2 weeks, when finally seeing my gp she referred me to a councillor, which took another 2 weeks before I saw them, only to be told they don’t have a clue at what stage my cirrhosis is?
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