Duodenal Ulcer :: PPI Side Effects - Dry Throat And Mouth With Metallic Taste


Feb 11, 2010

I was given lansoprazole due to a suspected stomach ulcer. I started taking it but was unable to continue to take the lansoprazole as it gave me a worse pain in my stomach than I already had and also a dry throat and mouth. I have now been diagnosed with h.pylori and started with triple therapy - esomeprazole (nexium)/amoxicillin/clarithromycin. The nexium isn't causing any stomach pain but is making my throat and mouth very dry and given me a sore throat and I am also suffering from a very unpleasant metallic taste in my mouth constantly. I went to the doctors again today and was given omeprazole to take instead but now I don't want to take it because I don't feel it will make much difference. Has anyone else had these side effects from the PPI and are there any alternatives I can take to inhibit the acid enough to let the antibiotics do their job?

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I noticed the following changes in my body when I experiencing some stress:

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5. Metallic taste in my mouth and weak gums.

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All of these seven symptoms occur simultaneously when I am late awake in the night or during stressful situations, and they are affecting my ability to function.

On a related note, I also experience sleep paralysis and hyperhidrosis but it is not simultaneous with the above symptoms.

I have noticed that these symptoms manifest themselves together. The restless legs problem occurs when there is urge to urinate (which is frequent) and I experience some relief after I urinate.

There is some bowel irritability and gastric problems which worsens during the night.

I have noticed that even at times when I do get my 8 hours of sleep in the day, I experience rage issues late in the night (at around 4-5 am) which recedes quickly in an hour or two.

I experience metallic taste in my mouth and a metallic smell in my fingers often. Other symptoms, such as gastric problems, urinary incontinence, and restless legs are almost always present when I am experiencing the metallic taste and smell.

The symptoms are relieved when I urinate (which I have to do quite often), brush my teeth, or sleep. They return quickly though when I am experiencing some level of stress.

The problems have been slowly worsening over the years and are interfering my ability to function normally.

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I have been trying to quit smoking since 2011 and have been a smoker since 1991.
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So I was wondering if someone who understands this coughing issue could be could shoot me an answer first.

I am meant to go to University tomorrow (I am studying for a Psychology Degree) and I want to be at my peak for study if at all possible.

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