Menopause :: Spotting In Meno Because Of Estrace?

I'm 55 and have been officially in menopause for about 4 years. My only difficulty has been severe vaginal dryness and atrophy (ugh, what a repellent word. Imagine if men referred to their penises as "Atrophic?").

I tried ignoring it. Tried some natural lubrications but those only worked at "the outer edges" (ahem) of the problem. I eat a very healthy diet, exercise, blah, blah, blah. In other words, I try. I really do.

So dutifully I tried Estrace cream: 4 grams a nite for 2 weeks. Then 2 grams a nite for 2 weeks. Then I was supposed to use it 2 times a week.

I had just arrived at the 2x a week when voila: spotting. It was just some pink (not much) when I wiped after peeing. Oh, at and the start just 1 suspicious itty bitty teeny tiny drop of blood, bright and alarmingly red.

Although the vaginal dryness was much improved, my breasts were swollen and tender (as if premenstrual) and I felt crampy and uncharacteristically irritable.

So, off to the gyno. Who today did a sonogram. Says my endometrium lining is "a bit thick" and next I must have an endometrial biopsy.

Have had 3 of them during the perimeno years when I was having random periods. And it really hurts. Now, with the atrophy and dryness, I'm terrified of the procedure.

And even more terrified of the possible results.

Has anyone out there ever had spotting on Estrace?

If so, when you stopped using it did it go away?

I avoid medication anytime humanly possible. Never much even bother to take aspirin for a headache. I'm very "natural" and prefer to keep it that way. But I did the Estrace because I was so miserable and my quality of life was diminished. Sex became out of the question, libido was gone and all I anticipated from a part of my body that I'd always delighted in....was pain. So I went against my own usual style and gave the Estrace a shot.

Now I'm frightened and anxious and wondering if any of you out there have been thru anything similar; and if so, what happened?